유리체내 베바시주맙 주사술 후 발생한 HLA‐B27 양성 급성 전방 포도막염 1예

• 영문명: A Case of Acute Anterior Uveitis Associated with HLA-B27 Positivity after Intravitreal Injection of Bevacizumab
• 발행기관: 대한안과학회
• 저자명: 서장원 권윤형,Jang Won Seo, MD, Yoon Hyung Kwon, MD
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume54,number12, 1945~1949쪽, 전체 5쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2013.12.13

영문 초록

Purpose: Intravitreal injection of bevacizumab (Avastin^{®) can lead to several intraocular complications including endophthalmitis, hemorrhage and inflammation. We present one case of acute anterior uveitis with hypopyon in an HLA-B27(+) patient following intravitreal injection of bevacizumab.
Case summary: A 40-year-old male with known central retinal vein occlusion presented with redness and decreased visual acuity in the left eye. Symptoms had developed 4 days earlier after the sixth intravitreal injection of bevacizumab in that eye. The patient had a marked anterior chamber reaction with hypopyon and posterior synechiae. Nine days after onset, similar symptoms in the left eye occurred in the uninjected right eye. Through examination and clinical manifestations, we diagnosed acute anterior uveitis associated with HLA-B27 positivity. The patient was treated with 1% prednisolone acetate, 0.5% moxifloxacin and 1% atropine in both eyes and all symptoms had resolved after 6 weeks.
J Korean Ophthalmol Soc 2013;54(12):1945-1949}

키워드

Acute anterior uveitis, Bevacizumab, HLA-B27 positive, Hypopyon, Intravitreal injection