유리체강내 덱사메타존 임플란트 삽입 후 발생한 급성 안내염 1예

• 영문명: A Case of Acute Endophthalmitis Following a Dexamethasone Intravitreal Implant
• 발행기관: 대한안과학회
• 저자명: 한현철 방종욱 염정훈 김진형 이도형 이종현,Hyun Cheol Han, MD, Jong Wook Bang, MD, Jung Hoon Yum, MD, Jin Hyoung Kim, MD,Do Hyung Lee, MD, PhD, Jong Hyun Lee, MD
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume54,number12, 1939~1944쪽, 전체 6쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2013.12.13

영문 초록

Purpose: To report a case of acute endophthalmitis after a dexamethasone (Ozurdex^{®) intravitreal implant for macular edema (ME) secondary to branch retinal vein occlusion (BRVO).
Case summary: A 63-year-old male patient presented with decreased vision in the right eye due to ME secondary to BRVO. The patient was treated with an intravitreal bevacizumab injection, but ME did not improve. Two months after the injection, dexamethasone (Ozurdex®) intravitreal implantation was performed. Four days after the implantation, the patient visited our clinic complaining of severe visual disturbance. Slight conjunctival injection was observed and inflammatory cells and hypopyon were found in the anterior chamber. Fundus was not visible due to vitreous opacity. The patient was presumed to have acute endophthalmitis. Vitrectomy, intravitreal antibiotics injection, dexamethasone implant removal and phacoemulsification were performed. After treatment, the patient’s fundus markedly improved, the inflammatory response was controlled and coagulase negative staphylococcus was detected from vitreous culture.
Conclusions: In cases of intravitreal dexamethasone implant associated with acute endophthalmitis, careful examination for diagnosis of endophthalmitis is recommended because the patient may not present with severe ocular pain and injection due to anti-inflammatory effect of corticosteroid.
J Korean Ophthalmol Soc 2013;54(12):1939-1944}

키워드

Branch retinal vein occlusion, Dexamethasone implant, Endophthalmitis, Intravitreal injection, Macular edema