펜타캠을 이용한 유리체강내 주입술 후 전방인자 변화 분석

• 영문명: The Change of Anterior Chamber Parameters with Pentacam; after Intravitreal Injection
• 발행기관: 대한안과학회
• 저자명: 김병선 김체론 김성재 한용섭 서성욱 유지명 정인영 박종문
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume54,number12, 1824~1831쪽, 전체 8쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2013.12.13

영문 초록

Purpose: To evaluate the changes of anterior chamber parameters and intraocular pressure (IOP) with Pentacam^{® after intravitreal injection.
Methods: A total of 76 eyes of 76 patients received an intravitreal injection of either triamcinolone acetonide (TA) or bevacizumab. Twelve patients were treated with an intravitreal injection of TA 0.1 ml, 16 patients were treated with an intravitreal injection of TA 0.05 ml, while the remaining 48 patients received a bevacizumab 0.05 ml injection. All patients underwent anterior chamber depth, anterior chamber angle, and anterior chamber volume evaluation with Pentacam® before and 5 minutes after injection. Additionally, IOP measurements were taken 5 minutes before and 5 minutes, 30 minutes, 1 hour and 1 day after injection.
Results: Anterior chamber depth, anterior chamber angle, anterior chamber volume, and IOP changes in patients receiving TA 0.1 ml were 0.4 ± 0.11 mm, 10.2 ± 4.1°, 33.7 ± 5.9 mm3 and 18.8 ± 12.1 mm Hg, respectively. Anterior chamber depth, anterior chamber angle, anterior chamber volume, and IOP changes in patients receiving TA 0.05 ml were -0.01 ± 0.05 mm, 2.4 ± 3.2°, 5.8 ± 9.5 mm3 and 4.8 ± 7.4 mm Hg, respectively. Anterior chamber depth, anterior chamber angle, anterior chamber volume, and IOP changes in patients receiving bevacizumab were 0.28 ± 0.99 mm, 0.8 ± 4.0°, 7.1 ± 9.6 mm3 and 5.4 ± 6.3 mm Hg, respectively. There was a significant difference between TA 0.1 ml and 0.05 ml. However, there was no significant difference between TA 0.05 ml and bevacizumab 0.05 ml.
Conclusions: Because of similar anterior chamber parameters changes after 0.05 ml intravitreal injection with TA or bevacizumab, early period IOP increases due to intravitreal volume expansion. Intravitreal 0.05 ml injections do not require any other procedures for controlling IOP 30 minutes after injection.
J Korean Ophthalmol Soc 2013;54(12):1824-1831}

키워드

Anterior chamber parameters, Intravitreal injection, Pentacam