건성안에서 인공누액제 점안이 중심각막두께에 미치는 영향

• 영문명: The Effect of Artificial Tear Application on Central Corneal Thickness in Dry Eye
• 발행기관: 대한안과학회
• 저자명: 서성관,Sung Gwan Seo, MD
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume50,number10, 1483~1488쪽, 전체 6쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2009.10.15

영문 초록

Purpose: To examine the effect of artificial tear use on central corneal thickness (CCT) in dry and normal eyes as a standard diagnosis for indicating dry eye. Methods: Thirty eyes of 30 patients with symptomatic dry eyes and 25 eyes of 25 controls were　examined in this study. Artificial tear therapy consisting of 6 drops/day was given to both groups for 2 weeks. The CCT was measured with ultrasonic pachymetry before and after the therapy. Results were analyzed with a paired t-test and Mann–Whitney U-test. Results: The mean CCT in the dry eye group before and after the 2 weekｓof therapy was 528.9±17.3 μm and　556±25.3 μm, respectively, which is an increase of 5.28% (27.1±9.2 μm, p <0.01). The mean CCT in the control group　before and after the ２ weeks of therapy was 546.3±36.5 μm and 549.6±39.3 μm, respectively, which is an increase of 0.61% (3.3±2.8 μm, p=0.08). Conclusions: The CCT in the dry eye group increased significantly compared to the eyes in the control group after use of artificial tears. The results indicate that the increase could be used as a standard in the　diagnosis and follow-up of dry eyes, and the increase in thickness should be considered in intraocular　pressure measurements as well as in refractive surgical procedures.

키워드

Artificial tear, Central corneal thickness, Dry eye, Pachymetry