검열반과 익상편 환자에서 눈물막과 안구표면의 변화

• 영문명: Changes of Ocular Surface and Tear Film in Patients with Pinguecula and Pterygium
• 발행기관: 대한안과학회
• 저자명: 오한진 박영걸 윤경철,Han Jin Oh, M.D., Yeoung Geol Park, M.D., Kyung Chul Yoon, M.D.
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume47,number5, 717~724쪽, 전체 8쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2006.05.31

영문 초록

Purpose: This study was performed to evaluate the parameters of tear function and ocular surface in patients with pinguecula and pterygium. Methods: The corneal sensitivity test (CST), tear break-up time (BUT), basal tear secretion test, fluorescein staining, rose bengal staining, tear clearance test, and conjunctival impression cytology were evaluated in patients with unilateral pinguecula and pterygium. The results were also evaluated according to the severity of pterygium. Results: In patients with pinguecula, BUT (P=0.03) and goblet cell density (P<0.01) were decreased, while the rose bengal staining score (P=0.01) was increased significantly. In patients with pterygium, CST (P=0.01), BUT (P<0.01), and goblet cell density (P<0.01) decreased, and the fluorescein staining score (P<0.01), rose bengal staining score (P<0.01) and grade of conjunctival metaplasia (P<0.01) increased significantly. In comparison with mild pterygium, moderate pterygium demonstrated decreased CST (P=0.01) and BUT (P=0.01), and an increased rose bengal staining score (P=0.04). Conclusions: The tear films and ocular surface changes in patients with pinguecula and pterygium are worse than in control group. Also, there is close correlation between the severity of pterygium and dry eye condition.

키워드

Ocular surface, Pinguecula, Pterygium, Tear film