갑상샘연관안와병증의 역학과 임상양상

• 영문명: The Epidemiologic and Clinical Characteristics of Thyroid-Associated Orbitopathy
• 발행기관: 대한안과학회
• 저자명: 고동아 김병진 MichaelKazim,Dong Ah Ko, M.D., Byoung Jin Kim, M.D., Michael Kazim, M.D.
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume47,number5, 683~689쪽, 전체 7쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2006.05.31

영문 초록

Purpose: To determine the epidemiologic and clinical characteristics of thyroid-associated orbitopathy (TAO). Methods: We retrospectively studied the clinical data of 385 patients from the New York City area diagnosed with TAO from January 1990 to December 2000. The total cases were divided into male and female groups and age-adjusted relative incidence rates were obtained to plot the incidence curve and clinical characteristics. Statistical analysis was applied to the collected data. Results: The average age of patients with TAO was 46.3 years for females and 50.1 years for males. The female-male ratio was 5.31:1. In 23.3% of patients, the diagnosis of TAO was made simultaneously with their thyroid disease. In 75% of cases, the diagnosis was made within 18 months of the presentation of thyroid disease. Soft tissue involvement was noted most frequently in 311 (80.8%), eyelid retraction in 306 (79.5%), proptosis in 278 (72.2%), restrictive myopathy in 234 (60.8%), and compressive optic neuropathy in 43 (11.2%) of 385 patients. Conclusions: TAO has variable and different epidemiologic and clinical characteristics according to sex and age.

키워드

Thyroid-associated orbitopathy (TAO), Thyroid ophthalmopathy, Epidemiology, Clinical characteristics.