새로운 세파로스포린 항생제 DA-074의 in vitro 항균력과 감염치료효과

• 영문명: In vitro Activities and in vivo Efficacies of DA-074 a New Cephalosporin
• 발행기관: 대한약학회
• 저자명: 최성학(Seong Hak Choi) 이태호(Tae Ho Lee) 김계원(Gye Won Kim) 김원배(Won Bae Kim) 이재걸(Jae Keol Rhee)
• 간행물 정보: 『약학회지』제44권 제4호 (2000년), 315~317쪽, 전체 3쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2000.08.30

영문 초록

The in vitro activities of DA-074, a new cephalosporin against 34 various standard strains and its in vivo efficacies against 6 important strains were obtained. DA-074 showed two fold enhanced in vitro antibacterial activity against some Pseudomonas aeruginosa compared to Ceftazidime and more than 2 fold in vivo efficacy against Staphylococcus aureus Smith, Klebsiella pneumoniae 1 and Eschetichia coli KC-14, compared to Cefpirome. DA-074 might be a good candidate for further evaluations.

키워드

DA-074 P. aeruginosa cephalosporin.