무우자갈버섯(Hebeloma crustuliniforme) 배양 균사체로부터 분리한 단백다당체 분획 HCA의 항암 및 백혈구감소증 억제효과

• 영문명: Antitumor and Antileukopenic Activity of HCA, the Protein-polysaccharide Fraction of Cultured Mycelia of Hebeloma crustuliniforme
• 발행기관: 대한약학회
• 저자명: 조경주(Kyung Joo Cho) 정경수(Kyeong Soo Chung)
• 간행물 정보: 『약학회지』제43권 제5호 (1999년), 629~634쪽, 전체 6쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 1999.10.28

영문 초록

A protein-polysaccharide fraction was isolated from the mycelial culture of a Korean basidiomycetous fungus, Hebeloma crustuliniforme, and was named HCA(Hebeloma crustuliniforme fraction A). When intraperitoneally injected at 200mg/kg/day once daily for 10 days, HCA inhibited the growth of sarcoma 180 solid tumor in ICR mice by 65.1%(p<0.05). HCA also exerted protective effect against leukopenia induced by cyclophosphamide with the protection ratio of 39.7%(p<0.01)

키워드

Hebeloma crustuliniforme polysaccharide HCA antitumor antileukopenic.