호장근의 사염화탄소로 유도된 지질과산화 저해활성

• 영문명: Antilipoperoxidant Activity of the Root of Polygonum cuspidatum on Carbon Tetrachloride Induced Hepatotoxicity
• 발행기관: 대한약학회
• 저자명: 김지연(Ji Youn Kim) 양기숙(Ki Sook Yang)
• 간행물 정보: 『약학회지』제43권 제5호 (1999년), 572~576쪽, 전체 5쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 1999.10.28

영문 초록

The root of Polygonum cuspidatum (Polygonaceae) has been used as treatments of hyper-lipidemia, dermatitis, gonorrhea, favus athlete's feet, inflammation in traditional medicine. In order to examine anti-lipidperoxidation activity, hexane, EtOAc, BuOH and water fractions of its methanol extract were administered to carbon tetrachloride intoxicated rats. Ethylacetate fraction exhibited antilipidperoxidative effect on liver lipid homogenate and the radical scavenging effect on DPPH. Serum transaminase, A/P, triglyceride and total cholesterol contents signigicantly decreased by administrations of ethylacetate fraction.

키워드

Polygonum cuspidatum Polygonaceae carbon tetra chloride antilipoperoxidant effect serum transaminase.