pH 의존성 Methacrylic acid 공중합체의 팽윤특성

• 영문명: pH-dependent Swelling Properties of Methacrylic Acid Copolymer Hydrogels
• 발행기관: 대한약학회
• 저자명: 김경충(Kyung Chung Kim) 이승진(Seung Jin Lee)
• 간행물 정보: 『약학회지』제33권 제6호 (1989년), 372~376쪽, 전체 5쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 1989.12.28

영문 초록

Equilibrium swelling and pH-sensitivity of a polyelectrolyte copolymer hydrogel were controlled by employing copolymers with different hydrophilic-hydrophobic balances. Model pH-sensitive hydrogels, e.g., poly(methacrylic acid), poly(methacrylic acid-co-acrylamide), poly(methacrylic acid-co-2-hydroxyethylmethacrylate), poly(methacrylic acid-co-styrene) were synthesized at various monomer compositions. As hydrophobicity of the copolymer hydrogels increased, the equilibrium swelling decreased while the pH-sensitivity increased. In the case of poly(methacrylic acid-co-acrylamide), polymer-polymer interaction significantly affected the equilibrium swelling and provided a wide range control of pH-sensitivity.

키워드

Equilibrium swelling pH-sensitivity copolymer hydrogel.