Octacosanol과 박과식물 추출물을 주성분으로 하는 혼합물의 지구력 증진 효과

• 영문명: Effect on Endurance Improving of Mixture of the Extracts of Watermelon and Octacosanol
• 발행기관: 대한약학회
• 저자명: 임현우(Hyun Woo Lim) 김성규(Sung Kyu Kim) 이민원(Min Won Lee)
• 간행물 정보: 『약학회지』제49권 제6호 (2005년), 465~470쪽, 전체 6쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2005.12.31

영문 초록

Octacosanol is known to enhance endurance activities, control cholesterol in body and improve the function of cardiopulmonary. Citrulline, which is main compound of watermelon, is known to improve angiectasia through stimulating production of nitric oxide. To improve endurance activity, swimming test on rats was carried out using four samples such as 1% octacosanol, citrulline, the extracts of barks of watermelon and products, mixture of 1% octacosanol and the extracts of barks of watermelon (6:4). Biochemical assays on the liver and serum of tested rats were also performed using commercial analysis kits. In result, it was shown that swimming time of Ⅲ group increased by 26% and that of Ⅴgroup was increased by 22% at the swimming test. As a result of biological assays on the liver and serum of tested rats, it was possible to confirm stability of toxicity. When compared with creatine kinase of control group(549.11±39.15 U/ℓ), citrulline (644.11±50.67 U/ℓ) and products group (646.00±46.99 U/ℓ) were largely increased. When compared with inorganic phosphate of control group (12.01±0.75 ㎎/㎗), citrulline (13.03±0.94 ㎎/㎗) and products group (12.90±0.55 ㎎/㎗) showed similar results. Also, when compared with lactic acid and glucose of control group (152.91±13.45, 103.00±8.69 ㎎/㎗), citrulline (125.53±15.54, 83.75±7.29 ㎎/㎗) and products group (135.26±11.50, 78.57±9.79 ㎎/㎗) were largely decreased. As these test results, it was determined that 1% octacosanol and extracts of barks of watermelon had some effect of improving endurance activity. Futhermore, it was thought that it could be used as source of functional food.

키워드

octacosanol citrulline watermelon endurance improving activity biological assays