수종 식물성 다당류의 사염화탄소 및 D-Galactosamine 유발 급성 간손상 보호작용

• 영문명: Protective Effects of Some Phytobased Polysaccharides on the Acute Hepatic Damages of ICR-Mice Induced by the Administration of Carbon Tetrachloride and D-Galactosamine
• 발행기관: 대한약학회
• 저자명: 문창규(Chang Kiu Moon) 안미영(Mi Young Ahn) 정진호(Jin Ho Chung)
• 간행물 정보: 『약학회지』제29권 제1호 (1985년), 43~49쪽, 전체 7쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 1985.02.28

영문 초록

Polysaccharides obtained from Sappan Lignum, Mori Radicis Cortex and Olibanum were examined for their liver protective effects against carbon tetrachloride- and D-galactosamine intoxication in ICR-mice. Hexobarbital sleeping time and serum transaminases (S-GOT and S-GPT) were measured as parameters for the evaluation of liver protective effects. All polysaccharides tested in this experiment showed remarkable positive effects on the prevention of hepatic intoxication with carbon tetrachloride- and D-galactosamine. Much better liver protective effects of polysaccharides were observed in D-galactosamine-liver injuries than in carbon tetrachloride-injuries.