회첨 엑기스의 혈압에 미치는 영향(II)

• 영문명: Effects of Siegesbeckiae Herba Extract on the Blood Pressure of Dogs and Chickens(II)
• 발행기관: 대한약학회
• 저자명: 김성원(Sung Won Kim) 고석태(Suk Tai Ko)
• 간행물 정보: 『약학회지』제24권 제2호 (1980년), 111~116쪽, 전체 6쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 1980.06.30

영문 초록

This study was performed in dogs and chickens to observe differences of responses by species of animals to hypotensive action of Siegesbeckiae Herba, using its ethanol extract. Siegesbeckiae Herba ethanol extract (SGEE), when injected into the vein of dogs or chickens, elicited depressor actions in both animals. The hypotensive effects of SGEE in dogs and chickens were markedly inhibited by the pretreatment of atropine, but not affected by bethanidine, propranolol and diphenhydramine. Phentolamine significantly weakened the action of SGEE in dogs, but did not alter the action of SGEE in chickens. SGEE inhibited the pressor action by norepinephrine or carotid artery occlusion, whereas it did not change the pressor action by angiotensin in dogs.