신생아 및 3개월 이하의 영아의 세균수막염의 임상적 양상과 치료결과

• 영문명: Clinical Manifestations and Treatment Outcome of Bacterial Meningitis in Neonates and Infants Under the Age of Three Months
• 발행기관: 대한소아신경학회
• 저자명: 박준석(Jun Seok Park) 김행미(Heng Mi Kim) 권순학(Soon Hak Kwon)
• 간행물 정보: 『Annals of Child Neurology(구 대한소아신경학회지)』대한소아신경학회지 제18권 제2호, 237~243쪽, 전체 7쪽
• 주제분류: 의약학 > 소아과학
• 파일형태: PDF
• 발행일자: 2010.11.30

영문 초록

Purpose : Bacterial meningitis in neonates and young infants is one of the most serious conditions that can lead to severe neurological sequelae despite the approp- riate treatment. This study aimed at evaluating the clinical manifestations and treat- ment outcomes in patients under the age of three months, who had been diagnosed with bacterial meningitis. Methods : A total of twelve patients with bacterial meningitis under the age of three months from January 1997 to June 2010 were retrospectively evaluated through a review of their medical records. Patients who showed positive culture results were included in the study. Results : A total of 12 patients (6 males and 6 females, mean age 44.2 30.0 days) ± were enrolled in the study. All patients had fever upon admission. But most of them were unremarkable upon physical examination (75%). Streptococcus agalactiae was the most common organism cultured from CSF (7cases; 58.3%). Six cases showed positive results on CSF culture as well as on blood culture. Cefotaxime and ampicilin/ sulbactam or cefotaxime and ampicilin were given as initial treatment with a mean treatment duration of 15.1 6.0 days. Neurological complications and sequelae inclu ± - ded subdural effusion and hearing disturbance in two cases (16.7%). Nine cases (75 %) showed excellent outcomes without neurological deficits, and none were left with a severe degree of sequelae. Conclusion : The study showed that neonates or young infants with bacterial meningitis almost always present with fever and that S.agalactiae was the most common causative organism. In addition, the final outcome for these patients may be improved with early and appropriate treatment.

목차

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대상 및 방법

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키워드

Meningitis Bacterial Streptococcus agalactiae Infant Newborn