한국형 양극성 장애 약물치료 알고리듬 2022: 급속 순환형

• 영문명: Korean Medication Algorithm Project for Bipolar Disorder 2022: Rapid Cycling
• 발행기관: 대한신경정신의학회
• 저자명: 정종현 박원명 우영섭 윤보현 서정석 추일한 양찬모 김원 이정구 심세훈 박성용 손인기 김문두 정명훈 전덕인
• 간행물 정보: 『신경정신의학』제61권 제3호, 204~213쪽, 전체 10쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 2022.08.31

영문 초록

Objectives This study revised the Korean Medication Algorithm Project for Bipolar Disorder2018 for rapid cycling. Methods Questionnaires to survey the expert opinion of medication for rapid cycling were completed by a review committee consisting of 87 Korean expert psychiatrists. The experts’ opinions ere classified into three categories based on the lowest category in which the confidence interval fell (6.5≤ for first-line, 3.5≤ for second-line, and 3.5> for third-line treatment). Results The first-line treatments were a combination of mood stabilizers and atypical antipsychotics, atypical antipsychotics monotherapy, or mood stabilizer monotherapy. Furthermore, amood stabilizer with lamotrigine therapy and an atypical antipsychotic with lamotrigine combinations was the first-line treatment for a depressive episode. The first-line medications in all episodeswere valproate, lithium, quetiapine, olanzapine, and aripiprazole. Risperidone was the first-linemedication in manic episodes and mixed states, and lamotrigine was the first-line medication fortreating depressive episodes. Conclusion Compared to the surveys in 2018, the preference for atypical antipsychotics andlamotrigine has increased, and the modalities as a second-line treatment are more diversified.

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키워드

양극성 장애 급속 순환형 Bipolar disorder Rapid cycling KMAP-BP 2022