경도인지장애 선별 평가를 위한 가상현실 인지기능평가의 개발: 예비 연구

• 영문명: Development of Virtual Reality Neurocognitive Test for Mild Cognitive Impairment: Preliminary Study
• 발행기관: 대한신경정신의학회
• 저자명: 강민재 노현웅 손상준 채헌주 최선우 이은 석정호 장수아 김우정
• 간행물 정보: 『신경정신의학』제61권 제3호, 186~195쪽, 전체 10쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 2022.08.31

영문 초록

Objectives Mild cognitive impairment (MCI) is known to have a high rate of progression to Alzheimer’s disease. Early detection and intervention of MCI are of great interest in psychiatric and socioeconomic aspects. There are various screening tools for MCI, but their sensitivity and specificity vary greatly. This study assessed the usefulness of virtual reality (VR) neurocognitive tests as an assessment tool for neurocognitive function deficit in MCI. Methods Both VR neurocognitive tests and conventional neurocognitive tests, including Mini-Mental State Examination (MMSE), Montreal Cognitive Assessment (MoCA), and the Seoul Neuropsychological Screening Battery (SNSB), were conducted, and 21 participants completed the tests. The test results of the MCI and normal groups were compared, and correlation coefficients between the VR neurocognitive tests and SNSB were examined. Results The mean VR neurocognitive test total score of the MCI participants was significantly lower than that of normal participants (30.0±1.0 vs. 36.9±6.4; p<0.001). There were no significant differences in the SNSB, MMSE, and MoCA scores between the two groups. The VR neurocognitive total score correlated significantly with the MMSE, MoCA, and SNSB total scores (r=0.61, r=0.54, r=0.50, respectively; p<0.05). The scores of the subdomains of VR neurocognitive tests showed significant correlations with those of MMSE, MoCA, and subdomains of SNSB, with VR executive function and visuospatial function scores showing significant correlations with the SNSB executive function (r=0.46; p<0.05) and visuospatial function (r=0.60; p<0.01) scores, respectively. Conclusion This preliminary study suggests that the VR neurocognitive test can be a feasible and realistic tool for assessing the subtle but complex cognitive deficits in MCI, emphasizing spatial reasoning and executive functions.

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키워드

경도인지장애 인지기능 신경심리검사 가상현실 기억력 주의력 집행기능 시공간 기능 Mild cognitive impairment Cognition Neuropsychological test Virtual reality Memory Attention Executive function Visuospatial function