학술논문
Perspectives on Bovine Milk-Derived Extracellular Vesicles for Therapeutic Applications in Gut Health
이용수 7
- 영문명
- 발행기관
- 한국축산식품학회
- 저자명
- Daye Mun Sangnam Oh Younghoon Kim
- 간행물 정보
- 『Food Science of Animal Resources』Food Science of Animal Resources 제42권 제1호, 197~209쪽, 전체 13쪽
- 주제분류
- 농수해양 > 식품과학
- 파일형태
- 발행일자
- 2022.01.31
4,360원
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국문 초록
영문 초록
Extracellular vesicles (EVs) are nanosized vesicles secreted from cells into the extracellular environment and are composed of a lipid bilayer that contains cargos with biological activity;such as lipids;proteins;mRNAs;and noncoding microRNAs (miRNAs). Due to their biological activity and their role in cell-to-cell communication;interest in EVs is rapidly increasing. Bovine milk is a food consumed by people of all ages around the world that contains not only a significant amount of nutrients but also EVs. Milk-derived EVs also exhibit biological activity similar to other source-derived EVs;and studies on bovine milk EVs have been conducted in various research fields regarding sufficient milk production. In particular;not only are the effects of milk EVs themselves being studied;but the possibility of using them as drug carriers or biomarkers is also being studied. In this review;the characteristics and cargo of milk EVs are summarized;as well as their uptake and stability;efficacy and biological effects as carriers;and future research directions are presented.
목차
Introduction
Cargo of Bovine Milk-Derived Extracellular Vesicles
Uptake and Stability of Bovine Milk-Derived Extracellular Vesicles
Drug Delivery as Biological Carrier of Bovine Milk-Derived Extracellular Vesicles
Therapeutic Effects of Bovine Milk-Derived Extracellular Vesicles
Other Functions in Human Health
Conclusion and Perspectives
Conflicts of Interest
Acknowledgements
Author Contributions
Ethics Approval
References
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