고엽제 노출군과 비노출군 노인에서의 신경인지기능 검사 결과 비교

• 영문명: Comparisons of Neuropsychological Characteristics of Elderly Subjects With Versus Without History of Agent Orange Exposure
• 발행기관: 대한신경정신의학회
• 저자명: 한승규(Seunggyu Han) 최진희(Jinhee Choi) 소형석(Hyung Seok So) 최하연(Hayun Choi) 전홍진(Hong Jin Jeon) 김진섭(Jinseob
• 간행물 정보: 『신경정신의학』제60권 제4호, 346~353쪽, 전체 8쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 2021.11.30

영문 초록

Objectives Agent Orange is a defoliant chemical that is widely known for its use by the U.S. military during the Vietnam War. It is known to be associated with the occurrence of various diseases in exposed subjects. However, few previous studies have focused on the effects of exposure to Agent Orange on cognitive dysfunction. Methods A total of 387 male subjects participated in the study. They were divided into those who were exposed to Agent Orange (n=301) and those without exposure (n=86). Both were evaluated with neuropsychological batteries, including the Consortium to Establish a Registry for Alzheimer’s Disease and the Seoul Neuropsychological Screening Battery-Second Edition. Results The group exposed to Agent Orange showed significantly higher scores in the Rey Complex Figure Test copy and recognition compared to those without exposure. Conclusion In this study, we compared the effects of exposure to Agent Orange on cognitive function in groups that had not yet progressed to dementia. The Agent Orange exposure group showed better results in some tests evaluating visuospatial and memory function.

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키워드

고엽제 인지기능 장애 심혈관계 위험인자 신경심리검사 Agent Orange Cognitive decline Cardiovascular risk factors Neuropsychological tests