위장관 향도잡이 세포

• 영문명: Pacemaker Cells in Gastrointestinal Tract
• 발행기관: 조선대학교 의학연구원
• 저자명: 최석(Seok Choi) 전제열(Jae-Yeoul Jun)
• 간행물 정보: 『The Medical Journal of Chosun University』제32권 제1호, 9~12쪽, 전체 4쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2007.02.28

영문 초록

The interstitial cells of Cajal (ICC) have functions o f pacemaker cells in gastrointestinal (GI) tract and neuromediator cells in the tunica muscularis of the GI tract. The ICC generate the rhythmic oscillations in membrane potential known as slow wave potentials and this generation of slow wave potentials is due to spontaneous inward currents called pacemaker currents. Although the exact mechanisms about these events still unclear, many reports suggested that the activation o f non-selective K+ channels, Cl channel, and spontaneous intracellular Ca2+activities in ICC involve the producing of pacemaker activity. Also, it is well known that many endogenous agents such as neurotransmitters, hormones, and paracrine substances modulate GI tract motility by influencing ICC.

목차

Interstitial cells of Cajal의 기능 및 종류

Interstitial cells of Cajal에서 기록 되는 자발적 내향성 전류(Pacemaker 전류)

Interstitial cells of Cajal의 임상적 중요성

앞으로의 실험방향

키워드

Interstitial cells of Cajal Gastrointestinal Tract Pacemaker currents