Drug resistant gastric cancer cells and their resistant mechanisms

• 발행기관: 조선대학교 의학연구원
• 저자명: Young-Don Min Chan-Guk Park Cheol-Hee Choi
• 간행물 정보: 『The Medical Journal of Chosun University』제33권 증보판, 36~42쪽, 전체 7쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2009.01.31

영문 초록

Gastric cancer is the second leading cause of death from malignant disease over the world. The combination chemotherapies have been empirically selected without considering drug resistance. Therefore, it is necessary that we have to think about rationales of combination chemotherapies on the basis of drug resistance. A large number of cancer cells have been selected for resistance to various drugs and characterized with respect to drug resistant mechanisms for long time. Nevertheless, there is so far no review that has summarized human drug resistant gastric cancer cells and their resistant mechanisms in details. Here we summarize drug resistant gastric cancer cells with references in terms o f tissue origin, publication year, nationality of an author, names of parental and drug resistant cells, resistance fold if possible and selecting drugs, and then discuss resistant mechanisms.

목차

Introduction

Discussion

Conclusion

키워드

gastric cancer drug resistance resistant cancer cells