인터페론-alpha2b로 치료한 흑색종 환자에서 발생한 양극성 증후군 - 증 례 보 고 -

• 영문명: Interferon-alpha2b Induced Bipolar Syndrome in Patient with Melanoma - A Case Report -
• 발행기관: 대한신경정신의학회
• 저자명: 홍순태 이선영 배재남 강민희 김철수 김철응
• 간행물 정보: 『신경정신의학』제43권 제4호, 481~484쪽, 전체 4쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 2004.07.30

영문 초록

The use of a high dose regimen of interferon (INF) has recently been demonstrated to benefit patients with malignant melanoma and the use of high dose INF for stage IIB and III melanoma was approved by Food and Drug Administration in 1995. The therapeutic benefits of INF are sometimes hampered by their severe and troublesome adverse effects including depression, mania, and cognitive impairment. The authors report a melanoma patient treated with adjuvant INF-alpha2b who developed a manic-depressive syndrome or mood instability with therapy and we reviewed literatures on mania and mixed affective syndrome associated with INF

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키워드

Interferon Melanoma Adverse effect Mania Mood instability