정신건강의학과 외래치료를 받고 있는 노인환자들의 다중약물요법과 연관된 약물사용양상과 요인들

• 영문명: Patterns of Drug Use and Factors Associated with Polypharmacy in Elderly Patients Visiting Psychiatric Outpatient Clinic
• 발행기관: 대한신경정신의학회
• 저자명: 정연경 이강준 김 현
• 간행물 정보: 『신경정신의학』제51권 제5호, 312~317쪽, 전체 6쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 2012.09.30

영문 초록

ObjectivesZZThe objective of this study was to investigate the patterns and recent trends in polypharmacy among elderly patients visiting psychiatric outpatient clinic. MethodsZZ289 elderly patients visiting psychiatric outpatient clinic were interviewed and their medical records were thoroughly reviewed. Inclusion criteria were as follows : 1) 65 years and older age patients, 2) diagnosed with one or more psychiatric disorder according to ICD-10 criteria, 3) who were willing to participate in this research. Demographic data and clinical data, including prevalence of polypharmacy, doses and types of drugs both prescribed and self-administered, were analyzed. Polypharmacy was defined as the long-term simultaneous use of six or more drugs. Data were statistically analyzed by t-test, analysis of variance, and simple regression analysis. ResultsZZ57.1% of the patients were prescribed with more than six drugs simultaneously. Mean number [±standard deviation (SD)] of psychiatric drug was 3.42±1.41. Prevalence of polyphamacy was different among psychiatric disorder groups, bipolar disorder group being the highest (mean±SD drug used=5.17±0.98). Regarding sedative-hypnotics, 59.5% of patients were prescribed (mean±SD drug used=2.02±1.07). Visual Analogue Scale (VAS) and total number of drugs prescribed were positively correlated (p<0.05). Herb medicine/dietary supplement had no influence on total number of used drugs. ConclusionZZElderly patients are suffering from many comorbidities and vulnerable to multiple drug use that can be potentially harmful, so it is important and essential to be aware of the possibility of polypharmacy and prescribe appropriate drugs to improve their quality of life.

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키워드

Polypharmacy Elderly Psychiatric outpatient