전기경련치료가 치료저항성 조현병 환자의 치료에 미치는 영향

• 영문명: Electroconvulsive Therapy for Patients with Treatment- Resistant Schizophrenia Patients : A Retrospective Study
• 발행기관: 대한신경정신의학회
• 저자명: 송태홍 심주철 공보금 강제욱 문정준 김성진 임지섭 김임규 정도운
• 간행물 정보: 『신경정신의학』제51권 제5호, 271~276쪽, 전체 6쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 2012.09.30

영문 초록

ObjectivesZZThis study analyzes the effect of electroconvulsive therapy (ECT) by predicting the factors contributing to the effectiveness of ECT and evaluating the persistency of ECT effect in patients with treatment-resistant schizophrenia. MethodsZZUsing retrospective review of the charts of 24 schizophrenic inpatients who were admitted to Busan Paik Hospital between March 1, 2005 and December 31, 2009. We compared the pre-ECT Clinical Global Impression (CGI) scores and post-ECT CGI scores among these patients. We evaluated the differences in the ECT responses by sex, age, duration of illness and dose of antipsychotic agents, and investigated the rate of continuation of out-patient treatment and readmission, and the change of the CGI score for 12 months after the ECT. ResultsZZECT resulted in an overall clinical improvement as measured on the CGI scale. 15 (62.50%) patients were good responders, while 9 (37.50%) were poor responders. There was no significant difference between sex, age, duration of the illness, and dose of antipsychotics taken by the patient before the ECT. 21 (87.50%) patients continuously visited the outpatient department for 12 month, and 14 (66.67%) of them maintained the ECT effect with medical treatment only and without readmission. ConclusionZZThis study showed that the ECT could be a useful treatment option for schizophrenic patients who are resistant to antipsychotics

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키워드

Electroconvulsive therapy Treatment-resistant schizophrenia Antipsychotics