노인 남성에서 체위성 폐쇄성수면무호흡증 환자와 비체위성 폐쇄성수면무호흡증 환자의 인지기능 비교

• 영문명: Comparison of Neurocognitive Functions between Positional Obstructive Sleep Apnea Patients and Non-Positional Obstructive Sleep Apnea Patients in the Korean Elderly Population
• 발행기관: 대한신경정신의학회
• 저자명: 김형찬 강석훈 최진희 정혜경 김태용 소형석
• 간행물 정보: 『신경정신의학』제54권 제4호, 564~569쪽, 전체 6쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 2015.11.30

영문 초록

ObjectivesZZObstructive sleep apnea (OSA) is classified as positional sleep apnea (POSA) and non-positional sleep apnea (NPOSA) according to apnea-hypopnea index (AHI) changed by sleep position. The aim of this study was to compare neurocognitive functions between two groups in the elderly Korean population. MethodsZZForty-four subjects in OSA patients with total AHI≥5 participated as criteria for POSA (n=25) with 1) supine position AHI/non-supine position AHI≥2 and 2) total AHI≥5 or not (NPOSA, n=19). All participants completed clinical interview by physician and neurocognitive function assessments. Mann-Whitney U and chi-square test were performed for comparison of neurocognitive functions and sleep characteristics with polysomnography between two groups. ResultsZZNo significant difference in demographic and clinical characteristics was observed between the two groups. However the NPOSA group showed more decline than the POSA group on the Boston naming test (p=0.034), digit span test (p=0.001), go-no-go test (p=0.042), and fist-edge-palm test (p=0.007). ConclusionZZIn this study NPOSA patients were found to have lower cognitive functions compared to POSA patients. A larger sample and long term follow-up study might be needed.

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키워드

Obstructive sleep apnea Sleep position Non-positional sleep apnea Polysomnography Neurocognitive function