생쥐의 강제수영시 부동자세시간과 통각예민도 간의 상관관계

• 영문명: Correlation between Pain Sensitivity and Duration of Immobility during Forced Swimming in Mice
• 발행기관: 대한신경정신의학회
• 저자명: 김길중 박제민 김명정
• 간행물 정보: 『신경정신의학』제30권 제4호, 686~693쪽, 전체 8쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 1991.07.31

영문 초록

The purpose of the study is to test by an animal experiment the hypothesis that pain insensitivity in depression is a trait marker rather than a state marker. 39 mice were studied for pain sensitivity by means of tail flick test before and after 6 minutes of forced swimming and for total duration of immobility during the last 4 minutes of forced swimming The correlation coefficients were calculated among the basal pain sensitivity, the change of pain sensitivity after forced swimming and duration of immobility during the forced swimming. The results are as follows. 1) A significant positive correlation was proved between the degree of pain insensitivity and duration o f immobility during forced swimming. 2) The forced swimming induced a significant pain insensitivity and a significant negative correlation was shown between duration of immobility and the change of pain sensitivity after forced swimming. From these results, the auther suggests that pain insensitivity in depression may be a trait marker rather than a state marker depending on the state of depression itself.

목차

서 론

실험대상 및 방법

실험결과

고 찰

요 약

References