²⁰¹Tl 게이트 심근관류 SPECT 및 심초음파의 좌심실 구혈률 상관관계 비교

• 영문명: The Correlation Analysis of Ejection Fraction: Comparison of ²⁰¹Tl gated Myocardial Perfusion SPECT and Echocardiography
• 발행기관: 대한핵의학기술학회
• 저자명: 윤순상(Soon Sang Yoon) 류재광(Jae Kwang Ryu) 차민경(Min Kyung Cha) 이종훈(Jong Hun Lee) 김성환(Sung Hwan Kim)
• 간행물 정보: 『핵의학기술』Vol.16 No.2, 49~56쪽, 전체 8쪽
• 주제분류: 의약학 > 방사선과학
• 파일형태: PDF
• 발행일자: 2012.10.30

영문 초록

Purpose : Gated myocardial perfusion SPECT provides not only myocardial perfusion status, but various functional parameters of left ventricle (LV). The purpose of this study was to analyze ejection fraction (EF) for correlation and difference between ²⁰¹Tl gated myocardial perfusion SPECT and echocardiography depending on extent of perfusion defect, gender and LV volumes. Materials and Methods : From April 2011 to May 2012, we analyzed 291 patients (male:female =165:126; mean: 64.6±10.8 years) who were examined both ²⁰¹Tl gated myocardial perfusion SPECT and echocardiography at less than 7 days apart in our hospital. 101 patients showed perfusion defect and the rest of the people without any defect. We applied automatic analysis (Quantitative gated SPECT, QGS), and calculated EF, End-diastolic volume (EDV) and End-systolic volume (ESV) from Stress (G-Stress) and Rest (G-Rest) studies. And we analyzed the correlation and difference for EF between ²⁰¹Tl gated SPECT and echocardiography. Results : The correlation of LVEF among G-Stress, G-Rest and echocardiography was quite a good (G-Stress vs. G-Rest: r=0.909, G-Stress vs. echocardiography: r=0.833, G-Rest vs. echocardiography: r=0.825). And there were significant differences in EDV, ESV and EF in total patients (p<0.01). The normal group showed significant difference in EF (p<0.01) and the group with perfusion defect also demonstrated significant difference (a group with reversible defect: p<0.01, fixed defect: p<0.01) depending on extent of perfusion defect. We analyzed difference in normal group by gender. In normal group, there was no significant difference (p>0.05) in EF from men. However, there was a significant difference (p<0.01) from women. When we classified two groups by average size of EDV in Korean women, there was no significant difference in a group of above average size of EDV (p>0.05). Conclusion : When compared among Stress and Rest of ²⁰¹Tl gated SPECT and echocardiography, we confirmed that there was a good correlation for LVEF. But there were significant differences among three studies. And extent of perfusion defect, gender and LV volumes are independent determinants of the accuracy of LVEF. So, it is hard to compare and interchange quantitative indices among modalities. We should take additional researches to prove results of our study.

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Introduction

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키워드

Myocardial perfusion SPECT Echocardiography Quantitative gated SPECT Ejection fraction