Association of Optic Disc Hyperfluorescence with Subclinical Macular and Optic Disc Edema in Uveitis Patients

• 영문명: Association of Optic Disc Hyperfluorescence with Subclinical Macular and Optic Disc Edema in Uveitis Patients
• 발행기관: 대한검안학회
• 저자명: Kunho Bae Chang Ki Yoon Eun Kyoung Lee Jae Hyup Lee Hyeong Gon Yu
• 간행물 정보: 『Annals of optometry and contact lens』Vol.21 No.4, 156~162쪽, 전체 7쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2022.12.31

영문 초록

Purpose: To investigate the frequency of optic disc hyperfluorescence (ODH) and their association with macular and optic nerve head thickness in patients with active uveitis. Methods: This retrospective cross-sectional study included 37 eyes of 30 patients with active noninfectious uveitis who underwent spectral domain-optical coherence tomography (OCT) and fluorescein angiography. OCT parameters were compared between baseline and post-treatment according to the ODH. Results: ODH was observed clearly in 22 eyes (64.7%) and equivocally in five eyes (14.7%) at baseline. In subgroup analysis without clinically significant optic disc edema, central subfield thickness, peripapillary retinal nerve fiber layer thickness, disc rim area, and disc area were 262.2 μm, 110.9 μm, 1.49 mm2, and 2.02 mm2 at baseline and significantly decreased after treatment (249.5 μm, 102.1 μm, 1.34 mm2, and 1.95 mm2, respectively) in eyes with ODH (p = 0.044, p < 0.001, p = 0.001, p = 0.024, respectively). However, there was no significant changes in the eyes without ODH (all p > 0.05). Conclusions: There was a difference in the thickness reduction of the macula and optic nerve head according to the ODH. Baseline ODH should be regarded as a sign of ocular inflammation and carefully monitored.

목차

INTRODUCTION

MATERIALS AND METHODS

RESULTS

DISCUSSION

REFERENCES

키워드

Fluorescein angiography Macular edema Optical coherence tomography Optic disc edema Uveitis