베바시주맙에 반응 않는 당뇨황반부종 환자에서 덱사메타존 삽입물의 수정체 내 주입 1예

• 영문명: Inadvertent Intralenticular Dexamethasone Implant for Diabetic Macular Edema Unresponsive to Bevacizumab
• 발행기관: 대한안과학회
• 저자명: 이효경 정세윤 한경은 신민철,Hyo Kyung Lee, MD, Se Yoon Chung, MD, Kyung Eun Han, MD, Min Chul Shin, MD, PhD
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume56,number1, 138~141쪽, 전체 4쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2015.01.15

영문 초록

Purpose: To report a case of inadvertent intralenticular slow-release dexamthasone implant (Ozurdex^{Ⓡ, Allergan Inc., Irvine, CA, USA) for diabetic macular edema unresponsive to bevacizumab. Case summary: A 71-year-old woman presented with proliferative diabetic retinopathy. During follow-up, diabetic macular edema developed in both eyes and did not improve with intravitreal bevacizumab injections. For refractory diabetic macular edema, slow-release dexamthasone implant (OzurdexⓇ) was to be injected at the vitreous cavity of her left eye, but it was inadvertently injected into the crystalline lens. The patient was followed closely for 10 months. Diabetic macular edema completely resolved 1 month after the injection and did not recur during follow-up. There were no severe complications except mild cataract formation. Best-corrected visual acuity for the left eye improved from 0.1 to 0.2. The OzurdexⓇ implant slightly decreased after 10 months, but was still observed in the crystalline lens. Conclusions: The inadvertent intralenticular dexamthasone implant was a rare complication but effective for diabetic macular edema. J Korean Ophthalmol Soc 2015;56(1):138-141}

키워드

Crystalline lens, Dexamethasone implant, Diabetic macular edema, Ozurdex