비접촉 마이봄샘촬영술을 이용한 한국인에서 연령에 따른 마이봄샘의 변화 연구

• 영문명: Changes of the Meibomian Gland According to Age in the Normal Korean Population
• 발행기관: 대한안과학회
• 저자명: 김주현 노진우 이가영 최동규 김하경 현준영 위원량 신영주
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume56,number1, 13~18쪽, 전체 6쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2015.01.15

영문 초록

Purpose: To examine the changes in meibomian glands associated with aging in a normal Korean population and to estimate the differences between the upper and lower eyelid in each age group. Methods: We performed meibography on adult subjects using an infrared charge-coupled device (CCD) camera. Each eyelid was scored based on the loss of meibomian glands, and the meiboscores of the upper and lower eyelids were summed to obtain a score for each eye. Meiboscores were evaluated according to age, sex, and upper and lower eyelid meiboscores in each age group. Results: One hundred seventeen eyes of 117 people were enrolled in this study. The study subjects had an average age of 50.4 ± 19.1 years (range, 20-92; male, 56; female, 61). There was a significant positive correlation between age and total meiboscore, upper and lower eyelid meiboscore (r = 0.578, p < 0.001; r = 0.550, p < 0.001; r = 0.524, p < 0.001). There were no significant differences in the meiboscores of the upper and lower eyelids in any age group, though meiboscores were significantly higher since 40 year-old group than 20 year-old group (p < 0.001, p < 0.001, p < 0.001, p < 0.001). Conclusions: Based on noncontact meibography in normal adult eyes, the authors concluded that prevalence of changes in the meibomian glands was about 60% and changes in meibomian glands increase with age. J Korean Ophthalmol Soc 2015;56(1):13-18

키워드

Meibomian gland, Meibomography, Meiboscore