한국인에서 포도막흑색종의 역학과 임상양상

• 영문명: Epidemiologic and Clinical Features of Uveal Melanoma in Korean Patients
• 발행기관: 대한안과학회
• 저자명: 배정훈 송원경 고형준 권오웅 이성철,Jeong Hun Bae, M.D., Won Kyung Song, M.D., Hyoung Jun Koh, M.D., Oh Woong Kwon, M.D., Sung Chul Lee, M.D.
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume49,number8, 1289~1296쪽, 전체 8쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2008.08.15

영문 초록

Purpose: To investigate the epidemiologic and clinical features of uveal melanomas in Korean patients. Methods: The medical records of 35 patients (35 eyes) with the diagnosis of uveal melanoma between September 2004 and December 2006 were reviewed retrospectively. Results: Of the 35 patients, 22 were males (62.9%) and 13 were females (37.1%), with a mean age at diagnosis of 48.2±14.1 years (range, 24-82 years). Decreased visual acuity was the most common symptom in 23 patients (65.7%), while 6 patients (17.1%) were detected without prior symptoms. The shape of the uveal melanoma was dome-shaped in 27 eyes (77.1%) and mushroom-shaped in 8 eyes (22.9%). The mean largest basal diameter of the tumors was 9.0±3.3 mm (2.4-19.0 mm), and the mean apical height was 6.2±2.6 mm (1.1-13.0 mm). The tumors were classified according to their size; a small melanoma was found in 4 eyes (11.4%), a medium melanoma in 29 eyes (82.9%), and a large melanoma in 2 eyes (5.7%). Conclusions: Uveal melanomas manifest earlier in Korean patients than in Caucasian patients. At the time of diagnosis, 33 eyes (94.3%) had small or medium melanomas that could be treated. J Korean Ophthalmol Soc 49(8):1289-1296, 2008

키워드

Clinical feature, Epidemiology, Korean patients, Uveal melanoma