당뇨황반부종에서 안구내 트리암시놀론 단독주입과 베바시주맙 병합주입의 단기 효과 비교

• 영문명: Intravitreal Triamcinolone Injection with or Without Bevacizumab for Diabetic Macular Edema
• 발행기관: 대한안과학회
• 저자명: 장민욱 김성우 오인경 오재령 허걸,Min Wook Chang, M.D., Seoung Woo Kim, M.D., In Kyung Oh, M.D., Jae Ryung Oh, M.D., Kuhl Huh, M.D., Ph.D.
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume49,number8, 1269~1274쪽, 전체 6쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2008.08.15

영문 초록

Purpose: To compare the effect of intravitreal triamcinolone injection with and without bevacizumab for diabetic macular edema. Methods: Of 69 patients (69 eyes) diagnosed with diabetic macular edema without any history of other intraocular disease or intraocular operation, 45 eyes (45 patients) were injected with intravitreal triamcinolone (4 mg) and the remaining eyes (24 patients) were injected with triamcinolone (2 mg) and bevacizumab (1.25 mg). The visual acuity and central macular thickness of treated eyes from both groups was measured using OCT, and these measurements were compared between the two groups. Results: There were no statistical differences between the two groups with respect to baseline data. Central macular thickness (CMT) was reduced in both groups, and BCVA improved in both groups. No significant differences were detected in changes in CMT or BCVA between the two groups. Conclusions: Intravitreal injection of triamcinolone had a beneficial effect on DME in terms of CMT reduction and BCVA improvement. Addition of three consecutive intravitreal bevacizumab injections, however, did not show any significant addictive effect during the follow-up period. J Korean Ophthalmol Soc 49(8):1269-1274, 2008

키워드

BCVA, Bevacizumab, CMT, Triamcinolone