결막과 비점막에 다발성 작은결절로 발현된 사르코이드증 1예

• 영문명: A Case of Sarcoidosis Presented as Multiple Conjunctival and Nasal Mucosal Nodule
• 발행기관: 대한안과학회
• 저자명: 유인천 문형진 문귀형 임상철 윤경철,In-Cheon You, M.D., Hyung-Jin Moon, M.D., Gwi-Hyeong Mun, M.D., Sang-Chul Im, M.D., Ph.D., Kyung-Chul Yoon, M.D., Ph.D.
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume49,number6, 1000~1006쪽, 전체 7쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2008.06.15

영문 초록

Purpose: Sarcoidosis is a noncaseating granulomatous disorder that can affect any organ. In its early phase, sarcoidosis is clinically similar to tuberculosis. We report a case of sarcoidosis diagnosed through ocular and systemic evaluations in a patient who developed multiple conjunctival nodules during antituberculous treatment for nasal mucosal nodules. Case summary: A 37-year-old woman who had been on antituberculosis medications for 9 months because of multiple nasal mucosal nodules was referred for conjunctival hyperemia and the multiple nodules. The ocular examination revealed multiple conjunctival nodules in the upper and lower fornices. Biopsy and systemic evaluations were performed. A conjunctival biopsy specimen showed noncaseating granulomatous inflammation compatible with sarcoidosis. Laboratory tests revealed hypercalciuria and increased levels of ACE. Chest computed tomography showed bilateral hilar and mediastinal lymphadenopathy. Subconjunctival steroid injection was done for the conjunctival nodules and systemic steroid treatment was started as well. Complete resolution of conjunctival lesions was obtained. Conclusions: In cases of chronic, multiple conjunctival and nasal mucosal nodules, sarcoidosis should be considered in the differential diagnosis. J Korean Ophthalmol Soc 49(6):1000-1006, 2008

키워드

Conjunctiva, Corticosteroid, Nasal mucosa, Sarcoidosis