유리체강 내 트리암시놀론 주입술 후 각막내피세포 변화

• 영문명: Corneal Endothelial Change After Intravitreal Triamcinolone Injection
• 발행기관: 대한안과학회
• 저자명: 류은혜 이정희 이수영 전루민,Eun Hye Ryu, M.D., Jeong-Hee Lee, M.D., Soo Young Lee, M.D., Roo Min Jun, M.D.
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume49,number6, 886~890쪽, 전체 5쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2008.06.15

영문 초록

Purpose: To evaluate the corneal endothelial cell changes after intravitreal triamcinolone (4 mg/0.1 ml, AcedoloneⓇ, Kuhnil) injection. Methods: From October 2006 to January 2007, 20 eyes of 19 patients who received intravitreal triamcinolone injection were enrolled. We analyzed the changes of the corneal endothelial cells prospectively and compared them with 11 phakic eyes (group 1) and 9 pseudophakic eyes (group 2) using specular microscopy. Results: The mean age of the patients was 65.9±8.5 years. The preoperative cell densities were 2534.1±303.6 in group 1 and 2105.9±328.0 in group 2 (p=0.01, Mann‐Whitney U test). The preoperative coefficients of variation of cell area were 34.6±9.7 in group 1 and 31.6±7.5 in group 2 (p>0.05), and the preoperative hexagonalities were 56.4±13.8 in group 1 and 66.4±20.4 in group 2 (p>0.05). The differences between preoperative and postoperative cell densities, coefficients of the variation of cell area, and hexagonalities were not statistically significant in either group (p>0.05). Conclusions: There was no clinically significant change in corneal endothelial cells after intravitreal triamcinolone injection. J Korean Ophthalmol Soc 49(6):886-890, 2008

키워드

Corneal endothelial cell, Triamcinolone