미숙아와 만삭아에서의 눈물막 기능과 눈표면 상태의 비교

• 영문명: Tear Function and Ocular Surface Findings in Premature and Term Babies
• 발행기관: 대한안과학회
• 저자명: 최계원 이해영,Gye Won Choi, M.D., Hae Young Lee, M.D.
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume47,number4, 531~537쪽, 전체 7쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2006.04.30

영문 초록

Purpose: To describe the ocular surface and tear function findings in premature and term babies. Methods: Sixty eyes of 30 premature babies and 60 eyes of 30 healthy term babies were studied. The subjects underwent routine ophthalmic examinations: corneal sensitivity test, corneal fluorescein test, Schirmer test with anesthesia, tear breakup time test, lipid layer pattern test and conjuctival impression cytology. Results: The mean corneal sensitivity scores were 35.2±5.0 mm and 54.2±3.7 mm in the premature and term babies, respectively (P<0.001). The mean Schirmer test score with anesthesia was 6.1±1.1 mm in the premature babies compared with 8.9±1.1 mm in the term babies (P<0.001). Premature babies had a mean lipid layer pattern score of 7.6±0.6 points, compared with 7.7±0.7 points in the term babies (P>0.001). Mean squamous metaplasia scores were 1.05±0.59 in the premature and 0.18±0.39 in the term babies (P<0.001). Conclusions: Premature infants had decreased tactile corneal sensitivity and reduced basal tear secretion as compared with full term infants. The premature infants did not have severe ocular surface disease from dry eyes because the lipid layers provide a protective effect for the ocular surface.

키워드

Dry eyes, Impression cytology, Premature infant