차가버섯 열수 추출물이 비장세포 증식능과 Cytokine 생성능에 미치는 영향

• 영문명: Effects of Hot Water Extract of Chaga Mushroom on the Proliferation and Cytokines Production of Mouse Splenocytes In Vitro
• 발행기관: 대한약학회
• 저자명: 김보라(Pora Kim) 고숙경(Suk-Kyung Ko) 표명윤(Myoung-Yun Pyo)
• 간행물 정보: 『약학회지』제54권 제3호 (2010년), 187~191쪽, 전체 5쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2010.06.30

영문 초록

Chaga mushroom (Inonotus obliquus) has been identified to have various biological activities. This study was performed to investigate the potential of chaga mushroom as a immunomodulating functional food. When mouse splenocytes were exposed to various concentration of hot water extracts of chaga mushroom (IOE) with mitogens (Con A, LPS), splenocytes proliferation was significantly increased. Also, IFN-γ and IL-4 levels were significantly enhanced. Therefore, our results suggest that chaga mushroom may have the potential of being an immunomodulating functional food.

키워드

Chaga mushroom Con A LPS IFN-y IL-4