음양곽 물추출물이 B16 Mouse Melanoma 세포의 멜라닌 생성에 미치는 영향

• 영문명: Effect of the Aqueous Extract of Epimedium Koreanum Nakai on Melanin Formation in B16 Mouse Melanoma Cell Line
• 발행기관: 대한약학회
• 저자명: 천현자(H J Chun) 문연자(Y J Mun) 김정훈(J H Kim) 김일광(I K Kim) 전병훈(B H Jeon) 우원홍(W H Woo)
• 간행물 정보: 『약학회지』제44권 제5호 (2000년), 455~462쪽, 전체 8쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2000.10.31

영문 초록

To investigate how the aqueous extracts of Epimedium koreanum Nakai (EK) affects pigmentation of skin, the aqueous extract of EK at various concentrations were incubated with 1 X 105 melanoma cells per well for 72h. The morphology and ntunber of cell line were not changed, but the aqueous extract of EK increased the tyrosinase activity and the content of melanin polymer in the cell line. These results indicate that the aqueous extract of EK promotes melanogenesis of B16 mouse melanoma cell line.

키워드

Aqueous Extract of Epimedium Koreanum Nakai(EK) melanin content tyrosinase activity.