안정동위원소 비율 및 테트라하이드로칸나비올 함량 분석을 통한 한국산 대마의 재배 환경 추론

• 영문명: Planting Condition of Korean Cannabis Derived from Stable Isotype Ratio & Tetrahydrocannabiol Contents
• 발행기관: 대한약학회
• 저자명: 이재신(Jae Sin Lee) 박용훈(Yong Hoon Park) 이종숙(Jong Sook Rhee) 정진일(Jin Il Jeong) 임미애(Mi Ae Lim) 정희선(Hee Sun Chung)
• 간행물 정보: 『약학회지』제52권 제3호 (2008년), 172~175쪽, 전체 4쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2008.06.30

영문 초록

Stable isotope ratio of carbon and nitrogen (δ13C & δ15N), and ∆ 9-tetrahydrocannabinol (THC) contents were measured on 37 Korean cannabis and 10 commercial grade marijuana seized in Korea. Factors influencing on the measured values and their variations were investigated. δ13 value of cannabis is specified mainly by water availability. Korean cannabis showed relatively low δ13 values ranging -33.29~-27.01‰ (mean=-31.01‰), which reflect geographic conditions of Korea where is rainy, especially during summer. δ15N values, which reflect individual planting conditions, were relatively high up to -0.5~18.0‰ (mean=6.44‰). It reflects characteristics of Korean cannabis growing wild in forest or cultivated in fertile soil. Tetrahydrocannabinol is the major hallucinogenic compound of cannabis. Ethanol extracts of cannabis leaves were derivatized by N,O-bis(trimethylsilyl)trifluoroacetamide (BSTFA), and the derivatives were analyzed by GC-MS in selected ion monitoring (SIM) mode. THC contents of Korean cannabis ranged 0.11~4.34% (mean=1.47%), which were relatively low compared with commercial grade marijuana.

키워드

cannabis marijuana stable isotope ratio tetrahydrocannabinol