TRH의 대량합성 제조법 개발

• 영문명: Process Development for Large Scale Synthesis of TRH
• 발행기관: 대한약학회
• 저자명: 김동현(Dong Hyeon Kim) 프리텀다빠(Pritam Thapa) 라다깔끼(Radha Karki) 장영동(Yurngdong Jahng) 이응석(Eung-Seok Lee)
• 간행물 정보: 『약학회지』제51권 제6호 (2007년), 490~494쪽, 전체 5쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2007.12.31

영문 초록

TRH (thyrotropin-releasing hormone) was chemically synthesized utilizing solution phase peptide chemistry for the process development of large scaled synthesis. All the synthetic steps performed in relatively mild conditions, higher yields, easier preparations, minimum racemizations, and separation and purification by recrystallizations.

키워드

TRH (thyrotropin-releasing hormone) process development peptide synthesis