황금 Baicalein의 위염 및 H. pylori 균에 미치는 효과

• 영문명: Antigastritic and Anti Helicobacter pylori Effects of Baicalein from Scutellaria Baicalensis
• 발행기관: 대한약학회
• 저자명: 강민희(Min Hee Kang) 이정헌(Jung Hun Lee) 이용수(Yong Soo Lee) 손건호(Kun Ho Son) 이동화(Dong Hwa Lee) 김영식(Yeong Shik Kim) 강삼식(Sam Sik Kang) 방효춘(Hyo Choon Bang) 정춘식(Choon Sik Jeong)
• 간행물 정보: 『약학회지』제51권 제1호 (2007년), 68~74쪽, 전체 7쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2007.02.28

영문 초록

Scutellaria Radix, the dried roots of Scutellaria baicalensis Georgi (Labiatae). has been used in oriental traditional medicine for treatment of fever, urine disorder, diarrhea, inflammation. Present study was carried out for the gastroprotective effect of chrysin, baicalcin, baicalin, wogonin wogonin from Scutellaria baicalensis. This reports evaluated antioxidant effect, antibacterial activity against Helicobacter pylori and HCl·ethanol-induced gastric lesion in rats and showed the significant effectiveness. It may be regarded that the antigastritic effects and antibacterial activity of baicalin, baicalein from scutellaria baicalensis are originated from acid-neutralizing capacity, free radical scavenging effects and the antibacterial activity against Helicobacter pylori.

키워드

baicalein Scutellaria baicalensis antigastritic acid-neutralizing capacity free radical scavenging effect H. pylori.