권백(Selaginella involvens) 물 추출물의 혈관 형성억제 및 혈관내피세포 이주 억제 효과

• 영문명: Inhibitory Effects of Water Extract of Selaginella involvens on the Tube Formation and Invasion of Human Umbilical Vein Endothelial Cells
• 발행기관: 대한약학회
• 저자명: 고유진(Yu Jin Ko) 박승희(Seung Hee Park) 이용화(Yong-Hwa Lee) 박병철(Byung Chul Park) 허종현(Jong Hyun Hur) 민용득(Yong Deuk Min) 김재기(Jae Ki Kim) 김정애(Jung-Ae Kim)
• 간행물 정보: 『약학회지』제51권 제1호 (2007년), 51~55쪽, 전체 5쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2007.02.28

영문 초록

Among pteridophytes, Selaginella involvens Spring and Equisetum arvense L. are used in folk medicine in Eastern Asian countries including Korea. The water extracts from Selaginella involvens Spring (SW) and from Equisetum arvense L (EW) did not affect viability of human umbilical vein endothelial cells (HUVECs). However, SW dose-dependently inhibited tube formation and migration of HUVECs, whereas EW did not. These results suggest that the water extract from Selaginella involvens Spring may have anti-angiogenic activity.

키워드

pteridophytes Selaginella involvens spring Equisetum arvense L angiogenesis tube formation migration