드로페리돌의 용출과 안정성에 미치는 결정형의 영향

• 영문명: Effects of Crystal Modification on Dissolution and Stability of Droperidol
• 발행기관: 대한약학회
• 저자명: 손영택(Young Taek Sohn) 정신희(Shin Hee Jung)
• 간행물 정보: 『약학회지』제40권 제4호 (1996년), 375~381쪽, 전체 7쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 1996.08.31

영문 초록

Five crystal modification of droperidol were prepared by recrystallization. They were characterized by UV spectrophotometer, DSC, and X-ray crystallography. Their dissolution patterns were also investigated. After storage of 2 months at 100% humidity, all polymorphic modifications were transformed.

키워드

Droperidol DSC, x-ray crystallography dissolution stability crystal modification humidity recrystallization.