새로운 플루오로퀴놀론계 항생제 LB20304a가 생쥐의 맹장내 세균총에 미치는 영향

• 영문명: Effect of a New Fluoroquinolone LB20304a on Microflora of Caecum in Mice
• 발행기관: 대한약학회
• 저자명: 안미정(Mi Jeong Ahn) 백경숙(Kyoung Sook Paek) 김무용(Mu Yong Kim) 김인철(In Chull Kim) 곽진환(Jin Hwan Kwak)
• 간행물 정보: 『약학회지』제40권 제3호 (1996년), 343~346쪽, 전체 4쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 1996.06.30

영문 초록

The influence of LB20304a, a new fluoroquinolone antibiotic agent, on microflora of caecum in mice was compared with those of ciprofloxacin and piperacillin after administration of drugs for 5 days. Selective medium (CCFMA) was used for the isolation of Clostridium difficile from the specimens of mouse caecum. The emergence of C. difficile in mouse caecum induced by LB20304a was lower than that by ciprofloxacin or piperacillin at day 1 and day 7 after completing administration of drugs.

키워드

LB20304a Fluoroquinolone Clostridium difficile Microflora.