새로운 퀴놀론 항균제 DW286의 살균작용

• 영문명: Bactericidal Activity of DW286, a New Fluoroquinolone Antibiotic
• 발행기관: 대한약학회
• 저자명: 윤희정(Hee-Jeong Yun) 민유홍(Yu-Hong Min) 심미자(Mi-Ja Shim) 최응칠(Eung-Chil Choi)
• 간행물 정보: 『약학회지』제47권 제6호 (2003년), 365~368쪽, 전체 4쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2003.12.31

영문 초록

The bactericidal activities of DW286, a new fluoroquinolone were investigated by comparing the minimal bactericidal concentrations (MBCs) and the time-kill curve of it against some Gram-negative bacterial strains. The MBCs of DW286 for the strains tested were either equal to or two-fold higher than the MICs, as were observed for the other fluoroquinolones. And DW286 exhibited rapid killing curves against the strains. Accordingly, it could be said that DW286 has bactericidal activity comparable to other fluoroquinolones.

키워드

DW286 fluoroquinolone bactericidal activity MIC MBC.