한국인 지방,간장 및 혈액 웅 유기염오제류 및 PCB congeners의 분포

• 영문명: Distribution of Organochlorines and PCB Congeners in Korean Adipose Tissue, Liver and Whole Blood
• 발행기관: 대한약학회
• 저자명: 유영찬(Young Chan Yoo) 이상기(Sang Ki Lee) 김기욱(Ki Wook Kim) 이수연(Soo Yeun Lee) 양자열(Ja Youl Yang) 김윤신(Youn Shin Kim) 오승민(Seung Min Oh) 정규혁(Kyu Hyuck Chung)
• 간행물 정보: 『약학회지』제46권 제4호 (2002년), 247~257쪽, 전체 11쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2002.08.31

영문 초록

Persistent organochlorine pesticides and polychlorinated biphenyls (PCBs) have been used intensively in agriculture or industry for a long time. The occurrence of organochlorine pesticides and PCBs in the environment and subsequently in parts of the food chain, resulting in the intake of these compounds by man and animal. The measure of the levels of organochlorine pesticides and PCBs in tissues or blood of human populations are good markers in determining the extent of exposure and in the evaluating the hazards. So, most countriess have conducted initial monitoring programs to determine organcchlorine pesticides and PCBs in human tissues. But a few report has been presented in Korea. In this study α-BHC, β-BHC,γ-BHC, δ-BHC, p,p'-DDT p,p'- DDD, p,p'-DDE, endrin, dieldein, aldrin and 7 marker PCBs (28,52, 101, 118, 138, 153, 180) were determined in human blood, adipose tissue and liver tissues collected at autopsy of 10 men and 10 women, 13-79 year of age. Significant differences in the levels of organochlorine pesticides and PCBs between districts where they had lived were found in the following chemicals : total PCB in the blood : β-BHC, total BHC, p,p'-DDE and total DDT in the adipose tissue : p,p'-DDE, total DDT and PCB 118 in the liver. No significant difference was fecund in the levels of organochlorine pesticides and PCBs between sexes and ages. Though the levels of organochlorine pesticides and PCBs were relatively lower than that of other countries, we could know that organochlorine pesticides and PCBs have been widely distributed in Korean human body.

키워드

PCB congeners Organochlorines Human tissues Korean GC/ECD.