HPLC를 이용한 제에웅의 레티놀 유도체 정량

• 영문명: Determination of Retinols in Pharmaceutical Preparations by HPLC
• 발행기관: 대한약학회
• 저자명: 안문규(Moon Kyu Ahn) 문현숙(Hyun Sook Moon) 허문희(Moon Hye Hur) 김대병(Dae Byung Kim) 박승희(Sung Hee Park)
• 간행물 정보: 『약학회지』제45권 제4호 (2001년), 357~365쪽, 전체 9쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2001.08.31

영문 초록

A simple and rapid determination of total retinol from various pharmaceuticals containing retinol derivatives was described. Retinol derivatives were hydrolyzed with alcoholic KOH to alcoholic retinol, which was determined by HPLC. Pretreatments and HPLC conditions depend on the kind of retinols and preparation forms. The total amount of alcoholic retinol could be determined with this method from many pharmaceutical preparation of retinol derivatives. Treating time of KOH, acidic reagents and HPLC conditions were investigated.

키워드

Retinol retinol derivatives HPLC.