인삼 사포닌이 일산화탄소와 노화에 의한 신경전달계 변화에 미치는 영향

• 영문명: Effect of Ginseng Saponins on Neurotransmitter System Damage in Carbon Monoxide and Aging Rats
• 발행기관: 대한약학회
• 저자명: 윤혜정(Hae Chung Yun) 신정희(Jeung Hee Shin) 최현진(Hyun Jin Choi) 윤재순(Jae Soo Yun)
• 간행물 정보: 『약학회지』제36권 제1호 (1992년), 56~65쪽, 전체 10쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 1992.02.28

영문 초록

The present study examined the effects of carbon monoxide (CO) intoxication and aging on learning and memory deficit in young (5~8 weeks) and aged (52~66 weeks) mice, using the step down and step through passive avoidance failure techniques. We also investigated the effects of ginseng saponins on memory deficit Significant decrease in memory registration, retention and retrieval function in young mice and decrease in memory registration and retention function in aged mice were observed. Normal young mice were apt to perform to a great degree of passive avoidance response than normal aged mice, but there was no difference between both groups by CO exposure, Administration of ginseng saponins showed an improvement on passive avoidance failure induced by CO exposure.