항생물질 현탁액중에서 Erythrosine의 흡수에 관한 연구

• 영문명: Studies on the Adsorption of Erythrosine in the Suspension of Antibiotics
• 발행기관: 대한약학회
• 저자명: 백우현(Woo Hyun Paik) 송영준(Yung Joon Song) 김정우(Jung Woo Kim) 김종갑(Johng Kap Kim)
• 간행물 정보: 『약학회지』제23권 제3&4호 (1979년), 133~140쪽, 전체 8쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 1979.12.30

영문 초록

The adsorption of erythrosine in the aliphatic alcohols by antibiotics such as ampicillin anhydrous, ampicilun trihydrate, amoxicillin trihydrate, cephalexin monohydrate was studied. The adsorption isotherms were all described with Freudlich equation. From the various experiments, it was found that the adsorption of erythrosine by antibiotics in the aliphatic alcohols was affected by the solubility of adsorbents. The adsoption in the mixture of aliphatic alcohols and water is related with the dielectric constant of mixed solvents. According to increase in the pH values of aqueous solution, the adsorption of erythrosine for antibiotics is decreased, but increased in the mixture of aliphatic alcohols and water. The adsorption of erythrosine in the suspension of antibiotics showed a correlation with the temperature. Colloidal silica which is used as stabilizer had a favorable effect on the adsorption of erythrosine in the suspension of antibiotics.