디아조크로마논과 보론산의 팔라듐 촉매하 결합반응을 이용한 Lespedezol A1의 합성

• 영문명: Formal Synthesis of Lespedezol A1 via Versatile Palladium-Catalyzed Cross-Coupling of Diazochromanone with Arylboronic Acid
• 발행기관: 대한약학회
• 저자명: 한영택
• 간행물 정보: 『약학회지』제57권 제5호 (2013년), 357~361쪽, 전체 5쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2013.10.31

영문 초록

A formal synthesis of Lespedezol A1 has been accomplished. The key feature of this synthesis involves an effi- cient and powerful palladium-catalyzed cross coupling reaction of diazocarbonyl compound with bis(benzyloxy)phenylboronic acid for the key 3-aryl-chromen-4-one intermediate, which was difficult to be prepared by Suzuki coupling reaction in the previous study. The versatile and efficient synthetic procedure would facilitate synthesis of pterocarpenes and their deriv- atives.

목차

재료 및 실험방법

실험결과 및 고찰

결론 및 고찰

감사의 말씀

참고문헌

키워드

Lespedezol A1 pterocarpene diazocarbonyl palladium cross-coupling