알츠하이머 치매와 경도인지장애에서 우울증상의 유병률과 특징

• 영문명: Prevalence and Characteristics of Depressive Symptoms in Alzheimer’s Disease and Mild Cognitive Impairment
• 발행기관: 대한노인정신의학회
• 저자명: 김윤아(Yoona Kim) 박기창(Kichang Park) 노현진(Hyunjean Roh) 김민혁(Min-Hyuk Kim)
• 간행물 정보: 『노인정신의학』노인정신의학 제17권 제2호, 79~85쪽, 전체 6쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 2013.12.31

영문 초록

Objectives：This study aimed to identify the characteristics of depression in early dementia and mild cognitive impairment patients. Methods：We included 412 community-dwelling elderly. They were assessed with Mini-Mental Status Examination in the Korean version of the CERAD Assessment Packet (MMSE-KC), Clinical Dementia Rating Scale (CDR), Korean version of Geriatric Depression Scale (GDS) and Korean version of Hamilton Depression Rating Scale (HDRS). All patients were divided three groups, nondemented group (ND), mild cognitive impairment group (MCI), and early dementia group (ED). We compared depressive symptoms between three groups using each items of HDRS. Results：Prevalence of depression (GDS≥16) was 24.6% in ND, 33.3% in MCI and 41% in ED. Several items of HDRS, depressed mood, feeling of guilt, loss of work & interests, psychomotor retardation, psychomotor agitation, psychic anxiety, somatic anxiety, and gastrointestinal symptoms, were significantly associated with cognitive decline in all subjects. However, no item of HDRS was significantly associated with cognitive decline in depressive patients. Conclusion：This study suggests that the prevalence of depression may increase as cognitive function declines. There was no difference in depressive symptoms between three groups.

목차

Abstract

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대상 및 방법

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키워드

알츠하이머병 경도인지장애 우울증상 치매 Alzheimer’s disease Mild cognitive impairment Depressive symptoms Dementia HDRS