이차성 조증과 전두피질하회로

• 영문명: Secondary Mania and Frontal-Subcortical Circuit
• 발행기관: 대한노인정신의학회
• 저자명: 정희정(Hee Jeong Jeong) 이영민(Young Min Lee)
• 간행물 정보: 『노인정신의학』노인정신의학 제17권 제2호, 56~60쪽, 전체 4쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 2013.12.31

영문 초록

Secondary mania is closely linked to neurocircuitry defects. Frontal-subcortical circuits, in particular, play a major role in the affective, motor and cognitive symptoms of secondary mania. In this paper, we present the three main frontal-subcortical circuits : the dorsolateral prefrontal circuit, which mediates executive functions (i.e., the organization of information to facilitate a response) ; the anterior cingulate circuit, which is involved in motivated behavior ; the orbitofrontal circuit, which has medial (i.e., integration of visceral-amygdalar functions with the internal state of the organism) and lateral divisions (i.e., integration of limbic and emotional information into contextually appropriate behavioral responses). Impaired executive functions, apathy, disinhibition and impulsivity are hallmarks of frontal-subcortical circuit dysfunction. The various neuropsychiatric manifestations of secondary mania may result from disturbances that have a direct or indirect impact on the integrity or functioning of these loops.

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키워드

양극성장애 후기발병 전두피질하회로 Bipolar disorder Late onset Frontal-subcortical circuits